Cloe® Screen
In vitro ADME screening service
Our in vitro ADME screening service offers a portfolio of assays for investigating: in vitro metabolism, in vitro permeability, solubility & physicochemical properties, protein binding and toxicity. Cloe® Screen delivers consistent, accurate compound data with cost-efficiency that comes from a highly automated approach.
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Cloe® Screen has passed evaluations by both large pharmaceutical and smaller biotechnology partners who now routinely use Cloe® Screen to support their drug discovery.
Cloe® Screen Services
| In vitro permeability |
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| PAMPA |
| Caco-2 permeability |
| MDCK (wild type) permeability |
| MDR1-MDCK permeability |
| Physicochemical properties |
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| turbidimetric solubility |
| thermodynamic solubility |
| CHI |
| log D |
| chemical stability |
| Protein binding |
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| plasma protein binding |
| Toxicity |
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| hERG channel inhibition (IC50 determination) |
Additional services are available - see Cloe® Select
Can't see the assay you need?
Please contact our Product Development Team with your requirements.
Request a quotation or
one of our publications.
Contact us for more information on Cyprotex, including our extensive range of ADME/PK services
and pricing.
