welcome to cyprotexcloe® screencloe® selectcloe® predict

Cloe® Select

Bespoke ADME and DMPK experimental service

Our Cloe® Select ADME and DMPK experimental service is designed to meet the requirements of later stage studies. Services include: in vitro metabolism, in vitro permeability, physicochemical properties and PK and bioanalysis. Cloe® Select offers the following benefits:

  • Flexibility - a portfolio of bespoke studies which can be customised to individual requirements.
  • Regulations - as with our Cloe® Screen ADME screens, our Cloe® Select service maintains and complies with regulatory guidelines providing constant confidence in the data received.
  • Results - a number of different reporting options are available from summary data to full written reports.
  • Consultancy - studies overseen by a single highly experienced and dedicated Principal Scientist who provides a high level of support and guidance prior to, during, and after the study.

Cloe® Select Services

In vitro metabolism
cytochrome P450 induction
cytochrome P450 Ki
UGT1A1 inhibition
metabolite profiling and identification
In vitro permeability
P - glycoprotein inhibition
Bioanalysis
bioanalytical method development and validation
Physicochemical properties
pKa and log P determination
Protein binding
brain tissue binding
blood to plasma ratio

Additional services are available under Cloe® Screen

Can't see the assay you need?

Please contact our Product Development Team with your requirements.

request

Request a quotation or
one of our publications.

Quotation   Catalogue
ADME guide
contact

Contact us for more information on Cyprotex, including our extensive range of ADME/PK services
and pricing.

contact
careerscontactlegalprivacy
This website was last updated
on 29th July 2010
This website is intended to assist investors, industry participants, customers and employees to understand Cyprotex’s global operations and ambitions.
Certain information and detail is disclosed in the interest of compliance of AIM Rule 26.