Cyprotex is a world renowned preclinical discovery/development contract research organisation with a core focus
in analysing the ADME (absorption, distribution, metabolism and excretion) and pharmacokinetic properties
of potential new drugs.

Cloe^® Screen: A high quality screening service which includes solubility, PAMPA, MDR1-MDCK permeability, Caco-2 permeability, cytochrome P450 inhibition, metabolic stability and hERG automated patch clamp.

Cloe^® Select: A bespoke experimental service focusing on later stage ADME and DMPK. It includes cytochrome P450 induction, K_i determination, metabolite profiling and identification, P-gp inhibition and blood to plasma ratio.

Cloe^® Predict: Expertise in predictive modelling using PBPK and QSAR techniques. Our proprietary software Cloe® PK predicts in vivo pharmacokinetics from in vitro ADME and physicochemical data.