In Silico
Cloe® PK - Pharmacokinetic prediction using PBPK modelling
Cloe® PK is an innovative software system that uses PBPK in silico modelling for pharmacokinetic simulation. The software integrates ADME and physicochemical data to simulate drug exposure and duration of drugs in blood, major tissues and organs as well as the prediction of key parameters such as absorption, clearance, half-life, volume of distribution and bioavailability.
Now available online via www.cloegateway.com
Cloe® HIA - Prediction of human intestinal absorption
Cloe® HIA is a reliable physiological model which uses a combination of solubility, pKa and Caco-2 permeability data for the prediction of human intestinal absorption.
Now available online via www.cloegateway.com
Auto QSAR and automation of laboratory workflow
The Cyprotex Discovery Bus is a novel and powerful software platform designed to enhance efficiency in drug discovery by automating human decision making and information handling using intelligent workflow. Applications include auto QSAR and automation of laboratory workflow processes.
Genomic ADME - gADME™
Cyprotex's proprietary gADME™ system can alert you to genetic variations in drug metabolism, allowing for personalised doses, drug rescue and repositioning.
Learn more about gADME
In vitro Micronucleus Test
Cyprotex now offers the in vitro micronucleus test for genotoxicity assessment using an automated, high content screening method for improved detection and reliability.
Learn more about our in vitro MNT service
Drug Transporters
Cyprotex provides a full range of drug-transporter studies as recommended by the ITC white paper and EMA guidelines.
Learn more about transporters
By Dr. Katya Tsaioun, Chief Scientific Officer, Cyprotex
Wiley & Sons, March 2011
