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9 August 2004

Holding(s) in Company

Cyprotex (the "Company")

The Company received notification on 29 July 2004 that, pursuant to the placing announced on 16 January 2004, Artemis Investment Management Limited holds 7,250,000 shares in the Company equating to 5.6947% of the issued share capital.

For further information:

Robert Morrisson Atwater, Chief Executive Officer
Cyprotex plc
Tel: +44 (0) 1625 505152
ir@cyprotex.com
www.cyprotex.com

News Contact:

Robert Morrisson Atwater, Chairman & CEO
+44 1625 505 152
ir@cyprotex.com
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