13 February 2007

Requisition of Extraordinary General Meeting

Cyprotex PLC ("the Company") received a requisition on 12 February, 2007 from Dr. David Leahy and Robert Long, being shareholders of the Company holding not less than one tenth of the paid up share capital of the Company, to hold an extraordinary general meeting of the Company pursuant to section 368 of the Companies Act 1985.

The purpose of the meeting is:-

1. to propose separate resolutions to remove each of Robert Atwater, Martial Lacroix, Minhaz Manji, David Evans, Nikolas Sofronis and Russell Gibbs as directors of the Company with immediate effect notwithstanding that the terms of their respective offices have not yet expired; and

2. to propose separate resolutions to appoint Dr. David Cavalla, Dr. David Leahy, Michael McGoun and Robert Long as directors of the Company with immediate effect.

The Board is seeking clarification from the requisitionists of the background to the requisition.

In the meantime the board is pleased to report that it has received indications of support from other shareholders representing more than 50% of the paid up share capital of the Company.

For further information:

Cyprotex PLC
Robert Morrison Atwater, CEO
Tel: +44 1625 505 100
ir@cyprotex.com
www.cyprotex.com

or

Russell Gibbs
Tel: +44 1625 505 100
ir@cyprotex.com
www.cyprotex.com

Nomura Code Securities Limited
Charles Walker
Tel: +44 (0)20 7776 1200
cew@nomuracode.com
www.nomuracode.com

Media Enquires:

WMC Communications
Charlie Geller/Alex Glover
Tel: +44 (0)20 7930 9030
charlie.geller@wmccommunications.com