Overview

How a drug is taken up and processed by the body will determine whether or not it will be effective. At Cyprotex, detailed profiles of potential drugs are generated to understand how they are absorbed, distributed, metabolised and excreted by the body. Collectively known as the ADME properties of a drug, this information is critical to drug researchers as they select and optimise new compounds during the drug discovery process.

Cyprotex's Cloe^® Technologies

Cyprotex's lead optimisation engine (Cloe®) is a novel combination of screening technologies, modelling tools and expertise that can be used by Pharmaceutical and Biotechnology companies to alleviate the problem of inappropriate pharmacokinetics, one of the major causes of attrition in drug discovery and development.

Cloe® enables our partners to improve the overall productivity of their research processes in three key ways:

Cyprotex is able to achieve this by applying computational prediction (Cloe® Predict) and high capacity experimental screening (Cloe® Screen) early in the drug discovery process when a large number of potential drugs are being evaluated.

A later stage bespoke experimental service (Cloe® Select) which is focused more at the drug development phase is also available at Cyprotex.