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Cyprotex's portfolio of experimental ADMET/PK services | Download
PDF (8.69 MB) |
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Cyprotex Drug Discovery Workshop Presentation: Identification
of Reactive Metabolites in Early Drug Discovery | Download
PowerPoint Slide Show (3.01 MB) |
|
Cyprotex Drug Discovery Workshop Presentation: Screening for
P-gp Inhibition In Vitro: Assays and Implications|
Download
Powerpoint Slide Show (4.37 MB) |
 |
DDT 2007 Conference Poster: Combination of in vitro
Caco-2 and Aqueous Solubility Screens with in silico
Physiological Modelling for the Prediction of Human Intestinal
Absorption in Early Drug Discovery| Download
PDF (4.15 MB) |
|
SBS Conference Poster: Cloe Screen MDR1-MDCK:
A predictive model of human intestinal absorption and blood
brain barrier permeability| Download
PDF (1.02 MB) |
|
SBS Conference Poster: Development of a high throughput
assay for the screening of mechanism-based CYP450 inhibition|
Download
PDF (1.21 MB) |
|
SBS Conference Poster: Combination of in vitro
Caco-2 and aqueous solubility screens with in silico
physiological modelling for prediction of human intestinal absorption
in early drug discovery| Download
PDF (0.98 MB) |
|
NC3Rs Poster Event - Computer Models for Replacing
Animal Kinetic Studies| Download
PDF (1.04 MB) |
|
Integrating in vitro ADMET data through
generic physiologically based pharmacokinetic models | Download
PDF (173 KB) |
|
9th European ISSX Meeting Poster - Development
of high-throughput PAMPA as an in vitro model of passive
transcellular permeation | Download
PDF (377 KB) |
|
9th European ISSX Meeting Poster - Development of
high-throughput assays for the screening of reversible and mechansim-based
cytchrome P450 inhibition by test compounds| Download
PDF (1.03 MB) |
|
Cyprotex's portfolio of experimental ADMET/PK services |
Download
PDF (3.06MB) |
|
Automated QSPR through Competitive Workflow. |
View
abstract |
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Application of a generic physiologically based
pharmacokinetic model to the estimation of xenobiotic levels
in human plasma.
| View
abstract |
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Application of a generic physiologically based
pharmacokinetic model to the estimation of xenobiotic levels
in rat plasma.
| View
abstract |
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Determination of a human hepatic microsomal scaling
factor for predicting in vivo drug clearance | View
abstract |
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Cloe® Screen Overview | Download
PDF (680kb) |
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Cloe® PK Overview | Download
PDF (476kb) |
|
|
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Outsourcing Discovery ADME Screening| Download
PDF (112kb) |
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Virtual Humans for Pharmacokinetics | Download
PDF (180kb) |
|
Cloe® PK White Paper | Download
PDF (177kb) |
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