Assessment of Neuronal Activity Using Microelectrode Array:

• The eCiphr^®Neuro assay uses primary cultures of rat cortical neurons.
• Cyprotex’s neuronal assay uses high throughput microelectrode array (MEA) technology to monitor electrophysiological activity.
• Neurons grown on microelectrode arrays recapitulate many features of neurons in vivo, including spontaneous activity (spiking and bursting), plasticity, organisation and responsiveness to a wide range of neurotransmitters and pharmacological agonists/antagonists¹.
• This technology provides a unique in vitro system for preclinical drug discovery, neurotoxicity assessment and disease modelling.

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