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- ADME PK
- ADME PK
- In Vitro Metabolism
- In Vitro Metabolism overview
- Reaction Phenotyping
- Cytochrome P450 Induction
- Relative Induction Score
- Cytochrome P450 (CYP) Inhibition (IC50)
- Cytochrome P450 Inhibition (Ki)
- Hepatocyte Stability
- Low Clearance HµREL Co-culture
- Low Clearance Hepatocyte Stability
- Hepatic Uptake Assay
- Metabolite Profiling and Identification
- Plasma Stability
- Microsomal Stability
- Microsomal Binding
- S9 Stability
- Time Dependent CYP Inhibition (single point)
- Time Dependent CYP Inhibition (IC50 shift)
- Time Dependent CYP Inhibition (kinact/KI )
- PXR and AhR Nuclear Receptor Activation
- UGT Inhibition
- In Vitro Permeability and Drug Transporter Services
- In Vitro Permeability and Drug Transporter Services overview
- PAMPA
- Caco-2 Permeability
- MDCK-MDR1 Permeability
- P-gp Substrate Identification
- BCRP Substrate Identification
- Human SLC Transporter Substrate Identification
- Human MRP Transporter Substrate Identification
- Preclinical Hepatic Oatp Substrate Identification
- P-glycoprotein Inhibition Service
- BCRP Inhibition Service
- Human SLC Transporter Inhibition
- BSEP, MRP2, MRP3 and MRP4 Inhibition
- Preclinical Hepatic Oatp Transporter Inhibition
- Non-CYP Mediated Metabolism
- Protein Binding
- Bioanalysis
- High Throughput ADME
- DDI Packages
- Prodrug Services
- Toxicology
- Toxicology
- Multiparametric Toxicity
- Immunotoxicology
- Mitochondrial Toxicity
- 3D Microtissue Models
- Hepatotoxicity and Drug-induced Liver Injury (DILI)
- Hepatotoxicity and Drug-induced Liver Injury (DILI) overview
- CellCiphr® Premier
- Cytotoxicity Screening Panel
- Drug Induced Phospholipidosis & Steatosis Assay
- Lysosomal Trapping
- BSEP, MRP2, MRP3 and MRP4 Inhibition
- Reactive Metabolite Assessment
- Cytochrome P450 Time Dependent Inhibition (IC50 Shift)
- Mitochondrial Toxicity
- Transcriptomics Services
- Genotoxicity
- 3D Hepatotoxicity Assay using HepaRG Spheroids
- Mechanistic Toxicity
- Mechanistic Toxicity overview
- Apoptosis and Necrosis Assay (Flow Cytometry)
- Cell Stress Panel
- Phospholipidosis and Steatosis
- Lysosomal Trapping
- Hemolysis
- DILIsym collaboration
- Reactive Metabolite
- Toxicological Gene Regulation
- Cell Viability
- KeratinoSensâ„¢ Skin Sensitization
- Androgen Receptor Modulation
- Phototoxicity
- Genotoxicity
- Neurotoxicity
- Cardiotoxicity
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Highlights
Cyprotex US, LLC is growing!
Our US site has expanded into a new facility in Framingham, MA
Regulatory DDI Studies
Full regulatory package of FDA, EMA and JMHLW recommended in vitro drug-drug interaction services
Cardiac and CNS MEA
Cyprotex are world leaders in the field of microelectrode array. Learn more about our cardiac and CNS assays.
3D Cell-based Models
Cyprotex are leading the science in the field of 3D cell-based technology. Our research has focused on the development of cardiac, liver, CNS and kidney models.
Latest news
February 15th 2023
Cyprotex US, LLC expands into new facility in Framingham, MA February 10th 2023
Evotec acquire € 150 m loan from European Investment Bank February 9th 2023
Evotec and Related Sciences amplify integrated drug discovery... 
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