Investigating Protein-Facilitated Uptake of OATP Substrates: From In Vitro Data to PBPK Modeling This September, Cyprotex, along […]
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- ADME PK
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- Relative Induction Score
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- Cytochrome P450 Inhibition (Ki)
- Hepatocyte Stability
- Low Clearance HµREL Co-culture
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- Hepatic Uptake Assay
- Metabolite Profiling and Identification
- Plasma Stability
- Microsomal Stability
- Microsomal Binding
- S9 Stability
- Time Dependent CYP Inhibition (single point)
- Time Dependent CYP Inhibition (IC50 shift)
- Time Dependent CYP Inhibition (kinact/KI )
- PXR and AhR Nuclear Receptor Activation
- UGT Inhibition
- In Vitro Permeability and Transporters
- In Vitro Permeability and Transporters overview
- PAMPA
- Caco-2 Permeability
- MDCK-MDR1 Permeability
- P-gp Substrate Identification
- BCRP Substrate Identification
- Human SLC Transporter Substrate Identification
- Human MRP Transporter Substrate Identification
- Preclinical Hepatic Oatp Substrate Identification
- P-glycoprotein Inhibition
- BCRP Inhibition
- Human SLC Transporter Inhibition
- BSEP, MRP2, MRP3 and MRP4 Inhibition
- Preclinical Hepatic Oatp Transporter Inhibition
- Polymorphic and Non-CYP Mediated Metabolism
- Protein Binding
- Bioanalysis
- High Throughput ADME
- DDI Packages
- Prodrug Services
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- 3D Microtissue Models
- Mitochondrial Toxicity
- Multiparametric Toxicity
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- Hepatotoxicity and Drug-induced Liver Injury (DILI) overview
- CellCiphr® Premier
- Genotoxicity
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- BSEP, MRP2, MRP3 and MRP4 Inhibition
- Lysosomal Trapping
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- 3D Hepatotoxicity Assay using HepaRG Spheroids
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- Apoptosis and Necrosis Assay (Flow Cytometry)
- Phospholipidosis and Steatosis
- Lysosomal Trapping
- Hemolysis
- DILIsym collaboration
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- Toxicological Gene Regulation
- Cell Viability
- KeratinoSens™ Skin $Sensitisation$
- Androgen Receptor Modulation
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