Regulatory | Cyprotex

Species Differences in Hepatic Uptake – A Focus on the Oatp Transporter

The most important OATP family member expressed in the human liver is OATP1B1, responsible for hepatic uptake […]

PK/PD modelling is an important aspect of dose prediction of antibiotics for both preclinical and clinical development […]

Drug-drug interactions (DDIs) can often be a complex mix of multiple mechanisms – therefore understanding the impact […]

The guidelines for the US FDA, EMA and Japanese PMDA are constantly evolving as our understanding of […]

It is astonishing to think that drug-drug interactions (otherwise known as DDI) account for at least 5% […]