Established in 1999, Cyprotex has over 150 staff based at its sites in the UK (Alderley Park in Cheshire) and in the USA (Watertown, MA). We operate as a contract research organisation and we have over 1700 customers worldwide within industries such as the pharmaceutical, cosmetics and personal care and the chemical and agrichemical markets. Outstanding customer service excellence and quality are key focuses of the business. In addition to our customer projects, we invest heavily in Research and Development of new techniques – many of these projects are exploring new in vitro or in silico methods to understand how chemicals or new pharmaceuticals may behave in humans in terms of their safety or efficacious effects.
Cyprotex is a growing and successful business and we are constantly recruiting for motivated and hardworking staff who thrive within a dynamic and vibrant organisation. We are committed to providing an environment where employees can learn and develop their skills and are recognised and rewarded for the contribution they make to the Company. Much of our work is performed in multi-disciplinary project teams that enables exchange of ideas and knowledge, enabling people to develop and take on additional responsibility either within the team or across teams in the business.
Watch our video to learn more about our UK facility at Alderley Park.
If you want to build your career with us, and contribute to our success, please send your CV to Human Resources.
We regularly advertise positions in disciplines such as ADME, in vitro toxicology, analytical sciences, in vitro biosciences, mathematical and physiological modelling, software development, finance and commercial / business development. Please view our current vacancies in the list below.
Cyprotex, part of the Evotec Group, are looking to appoint an Associate Principal Scientist to join our highly successful and progressive in vitro Toxicology Group based at Alderley Park, Cheshire, UK.
It’s the calibre of our people that creates our success and this role would be ideal for an experienced and innovative individual who thrives in a fast-paced commercial environment. The role will involve the proactive leadership of others, the opportunity to contribute to innovation/R&D activities as well as delivering high quality assay data for our customers plus oversight of a Horizon 2020 grant-funded project.
Primary Purpose:
Provide excellent scientific, technical and managerial leadership by setting aligned goals to drive performance and creating a positive climate for development and growth of colleagues.
Managing a sub group of the department on a day-to-day basis and provide strong guidance and expertise to facilitate the attainment of project and business goals. Supervise, coordinate and review the work of direct reports to ensure high research quality thereby achieving high customer satisfaction levels
Train and develop staff in experimental and scientific processes and provide scientific direction and line management to staff.
Support colleagues and customers by acting as scientific advisor, helping to interpret data and plan studies. Provide pricing and technical assistance for quotes for bespoke and new assays.
Drive R&D within the team and identify wider opportunities across Cyprotex.
Accountable for all aspects of the grant-funded project including designing experiments, collaborating with other partners, overseeing work performed at Cyprotex and reporting of results and administrative tasks to the consortium. Attendance at meetings within Europe will be required from time to time.
Responsibilities:
Our Ideal Candidate
PhD in in vitro toxicology, or related subject, along with considerable experience from working within Industry (Pharma or CRO).
Practical skills and techniques relevant to in vitro toxicology including cell culture, high content imaging analysis, flow-cytometry and mechanistic toxicology assays is essential.
Strong data analysis and interpretation skills with evidence from key publications in the field.
Line management and project management experience.
Skills & Competencies
Cyprotex, part of the Evotec Group, are recruiting for a highly organised Administration Assistant to join our Project Management team based at Alderley Park, Cheshire, UK.
It’s the calibre of our people that creates our success so we’re looking for a highly self-motivated individual to support the Project Management team on a full time, permanent basis.
The ideal candidate will be a team player with the ability to work collaboratively and effectively in a fast-paced, high-energy environment, across multidisciplinary teams, who has user experience of Salesforce or a similar customer relationship management system (CRM).
Primary Responsibilities:
To provide administrative support to the Project Management Team.
To ensure all study documentation is accurately recorded on the CRM and ShareFlex systems
To assist with the checking of pricing tables and protocols on study documentation
To support document retrieval for client audits
To compile ad-hoc reports from the CRM
To support the finance reconciliation process at month end
Additional Responsibilities
Knowledge Skills and Experience:
Essential
CRM experience, ideally with Salesforce
Experienced systems user, predominately Microsoft Office Outlook, Word, Excel, Teams and PowerPoint; intermediate level as a minimum.
Desirable
Proactive, experienced Administrator with excellent organisational and communication skills, both written and verbal
Ability to work accurately and with attention to detail, demonstrating a strong work ethic
Positive attitude; adaptable and flexible approach to work requirements, during periods of high volume
Excellent timekeeping skills
Must be a team player and also be able to work with minimum supervision
Rewards & Benefits:
Cyprotex aims to encourage, support and recognise the excellent performance and behaviour of our colleagues. Our performance-based compensation policy applies to all colleagues of the Evotec Group companies. We offer a variety of benefits and these include, amongst others, excellent pension benefits and service related holidays. We recognise that our colleagues have full lives away from the workplace and support working patterns that balance private life and career.
Career Development:
As part of the Evotec Group, we grow through innovation, collaboration, nurturing our people and continuing to develop as a world-class organisation.
Our work is challenging and requires the most competent staff, therefore we aim to recruit and retain the best. We look for talented individuals from all walks of life, educational backgrounds and nationalities to provide the expertise and dedication to enable us to continually achieve success in all that we do. We offer equal opportunities for people with or without, visible or not-visible disabilities.
If you are interested in this exciting opportunity please apply here.
Closing date for application is Friday 15th January 2021.
Cyprotex, part of the Evotec Group, are recruiting for an Associate Scientist to join our Physical Chemistry team based at Alderley Park, Cheshire.
It is the calibre of our people that creates our success. The successful individual will be required to work closely with other laboratory staff to ensure that experimental aspects of in vitro Physical Chemistry assays are safely performed to a high standard and within scheduled timelines.
Key Responsibilities or Core Accountabilities
Responsible for performing high quality Physical Chemistry measurements in protein binding, aqueous solubility, lipophilicity and chemical stability assays, either alone or as part of a team, within specified time frames.
Responsible for performing data analysis and data interpretation in accordance with defined procedures.
Responsible for performing routine laboratory-based tasks including:
Performing validation and routine maintenance of laboratory equipment.
Contributing to the maintenance of a clean and safe environment.
Management and ordering of stock consumables.
May be required to assist with the conduct of R&D and non-routine assays.
May be required to support our Quality System via preparation and maintenance of Standard Operating Procedures.
Knowledge, Skills & Capabilities
Highly organised with a strong level of attention to detail.
Establishes constructive and collaborative relationships with immediate colleagues, and passes on information promptly, keeping colleagues up to date.
Makes sure that work and/or assigned tasks are completed in an accurate and timely way.
Able to adapt to regularly changing priorities.
Digests and organises information in order to make clear decisions.
Ability to overcome obstacles and demonstrate persistence.
Education, Qualifications and Experience
A minimum of a BSc or equivalent in a relevant area of life science.
Direct experience in Physical Chemistry assays such as protein binding, aqueous solubility, lipophilicity or chemical stability is not essential but an understanding of the wider relevance of these parameters and the experimental factors that influence such measurements is preferred.
Direct experience of working with automated liquid handling systems, liquid chromatography and mass spectroscopy instruments is preferred but not essential.
Computer literate with experience of using Microsoft Office
Rewards & Benefits:
Cyprotex aims to encourage, support and recognise the excellent performance and behaviour of our colleagues. Our performance-based compensation policy applies to all colleagues of the Evotec Group companies. We offer a variety of benefits and these include, amongst others, excellent pension benefits and service related holidays. We recognise that our colleagues have full lives away from the workplace and support working patterns that balance private life and career.
Career Development:
As part of the Evotec Group, we grow through innovation, collaboration, nurturing our people and continuing to develop as a world-class organisation.
Our work is challenging and requires the most competent staff, therefore we aim to recruit and retain the best. We look for talented individuals from all walks of life, educational backgrounds and nationalities to provide the expertise and dedication to enable us to continually achieve success in all that we do. We offer equal opportunities for people with or without, visible or not-visible disabilities.
If you are interested in this exciting opportunity please apply here.
Closing date for application is Friday 15th January 2021.
Cyprotex, part of the Evotec group are recruiting an LC-MS/MS Scientist to join our Bioanalytical Team based at Alderley Park, Cheshire, UK.
Reporting to the Senior Research Scientist within the Bioanalytical group, ideally, we are looking for an individual with some LC-MS/MS bioanalysis experience interested in their next lab-based role within a fast-paced commercial environment. A minimum of a BSc in a relevant field, 2 years relevant experience in a bioanalytical position and excellent organisational skills are required. The role might also suit a recently qualified and motivated PhD Graduate.
Primary Duties:
The primary duties include but are not limited to:
LC-MS method development for a range of challenging compounds being assessed in discovery PK studies.
Organisation and Conduct of sample analysis to support discovery PK studies from booking in samples through to data reporting including all aspects of LC-MS analysis and data evaluation.
Overall responsibility for data quality on specific studies.
Troubleshooting and system maintenance on triple quadrupole or triple TOF instrumentation and co-ordination of engineer visits.
Day to day laboratory tasks including ordering, equipment maintenance and calibration.
Contributing to our Quality System via preparation of SOPs
To make a leading contribution in the development of new technologies and improvements to the current analytical capabilities at Cyprotex.
Knowledge, Skills and Abilities
Essential:
A good knowledge of bioanalytical techniques as applied to small molecules, peptides and oligonucleotides.
Experience of working with LC-MS/MS techniques in support of pre-clinical small molecule assays.
A high level of attention to detail.
Well organised with an ability to work without close supervision and lead bioanalytical projects.
Ability to adapt to changing priorities, manage multiple activities simultaneously and to achieve timelines.
Motivational team player with a high level of dedication.
Extensive computer literacy including use of Microsoft Office
Ability to rapidly learn new techniques and processes.
Preferred but not essential
Experience with MassLynx™ and Analyst™ software packages.
A wider knowledge of analytical support in drug discovery/development is also desirable.
A knowledge of DMPK/ADME assays within drug discovery desirable.
Qualifications
Minimum BSc in relevant scientific discipline covering chemistry.
Rewards and Benefits
Cyprotex aims to encourage, support and recognise the excellent performance and behaviour of our colleagues. Our performance-based compensation policy applies to all colleagues of the Evotec Group companies. We offer a variety of benefits, which include amongst others, excellent pension benefits and service related holidays. We recognise that our colleagues have full lives away from the workplace and support working patterns that balance private life and career.
Career Development
As part of the Evotec Group, we grow through innovation, collaboration, nurturing our people and continuing to develop as a world-class organisation.
We aim to recruit and retain the best because our work is challenging and requires the most competent staff. We look for talented individuals from all walks-of life, educational backgrounds and nationalities, to provide the expertise and dedication to enable us to achieve continual success in everything we do. We offer equal opportunities for people with or without, visible or not-visible disabilities.
If you are interested in this exciting opportunity, please apply here. The closing date for receipt of applications is 5pm on Friday 18th December 2020.
Direct applications only – no agencies please.
We are looking for applications for a senior scientific role (Associate Principal Sscientist/Senior Laboratory Supervisor) within the Physical Chemistry team, based at our site at Alderley Park, Cheshire.
The successful candidate will have significant experience in designing, validating, conducting and troubleshooting in vitro assays and of leading and mentoring a team of scientists. They will have a passion and aptitude to drive innovation and implement changes within the team and be a strong supporter of integrating the latest science and technology into the team’s workflows. In return, we offer a fascinating variety of work at the cutting edge of science, plus a salary commensurate with relevant experience.
Key Responsibilities or Core Accountabilities
Knowledge, Skills & Capabilities
Education, Qualifications and Experience
Cyprotex, part of the Evotec group are recruiting an LC-MS/MS Associate Scientist to join our Bioanalytical Team based at Alderley Park, Cheshire, UK.
Reporting to the Senior Research Scientist within the Bioanalytical group, ideally, we are looking for an individual with some LC-MS/MS bioanalysis experience interested in their next lab-based role within a fast-paced commercial environment. A minimum of a BSc in a relevant field and excellent organisational skills are required. The role might also suit a recently qualified and motivated Graduate.
Primary Duties:
The primary duties include but are not limited to:
LC-MS method development for a range of compounds being assessed in discovery PK studies
Conduct sample analysis to support discovery PK studies from booking in samples through to data reporting including all aspects of LC-MS analysis and data evaluation
Bespoke method development for compounds being assessed in invitro studies where generic methods are not successful
Troubleshooting and system maintenance on triple quadrupole or triple TOF instrumentation and co-ordination of engineer visits
Day to day laboratory tasks including ordering, equipment maintenance and calibration.
Contributing to our Quality System via preparation of SOPs
To aid in the development of new technologies and improvements to the current analytical capabilities at Cyprotex.
Knowledge, Skills and Abilities
Essential:
A good knowledge of bioanalytical techniques as applied to small molecules, peptides and oligonucleotides.
Experience of working with LC-MS/MS techniques in support of pre-clinical small molecule assays.
A high level of attention to detail.
Well organised with an ability to work without close supervision.
Ability to adapt to changing priorities, manage multiple activities simultaneously and to achieve timelines.
Motivational team player with a high level of dedication.
Extensive computer literacy including use of Microsoft Office
Ability to rapidly learn new techniques and processes.
Preferred but not essential
Experience with MassLynx™ and Analyst™ software packages.
A wider knowledge of analytical support in drug discovery/development is also desirable.
A knowledge of DMPK/ADME assays within drug discovery desirable.
Qualifications
Minimum BSc in relevant scientific discipline covering chemistry.
Rewards and Benefits
Cyprotex aims to encourage, support and recognise the excellent performance and behaviour of our colleagues. Our performance-based compensation policy applies to all colleagues of the Evotec Group companies. We offer a variety of benefits, which include amongst others, excellent pension benefits and service related holidays. We recognise that our colleagues have full lives away from the workplace and support working patterns that balance private life and career.
Career Development
As part of the Evotec Group, we grow through innovation, collaboration, nurturing our people and continuing to develop as a world-class organisation.
We aim to recruit and retain the best because our work is challenging and requires the most competent staff. We look for talented individuals from all walks-of life, educational backgrounds and nationalities, to provide the expertise and dedication to enable us to achieve continual success in everything we do. We offer equal opportunities for people with or without, visible or not-visible disabilities.
If you are interested in this exciting potision, please apply here. The closing date for receipt of applications is 5pm on Friday 18th December 2020.
Direct applications only – no agencies please.
Primary Responsibilities:
The primary responsibilities include but are not limited to:
Additional Responsibilities may include:
Knowledge, Skills and Abilities
Essential:
Preferred but not essential
Qualifications
Cyprotex, part of the Evotec Group, are recruiting for a Scientist to join our Physical Chemistry team based at Alderley Park, Cheshire.
It is the calibre of our people that creates our success, and this position would be ideal for an individual with previous experience working in a laboratory environment, ideally with knowledge of physicochemical properties. The successful individual will be required to work closely with other laboratory staff to ensure that experimental aspects of in vitro Physical Chemistry assays are safely performed to a high standard and within scheduled timelines.
Key Responsibilities or Core Accountabilities
Responsible for the design and execution of Physical Chemistry measurements in protein binding, aqueous solubility, lipophilicity and chemical stability assays, either alone or as part of a team, to a high standard and within specified time frames.
Responsible for processing and checking data, using scientific knowledge in analysis and interpretation, and problem solving where necessary.
To carry out assay development, validation and bespoke assays, with the support of senior team members.
Assay management; responsible for planning and data delivery of particular assays within the team, communicating effectively within the team and with client management.
Responsible for performing routine laboratory-based tasks including:
Performing validation and routine maintenance of laboratory equipment.
Contributing to the maintenance of a clean and safe environment.
Management and ordering of stock consumables.
Coaching of less experienced colleagues on assay execution and data analysis.
Supporting our Quality System via preparation and maintenance of Standard Operating Procedures.
Knowledge, Skills & Capabilities
Good understanding of physical chemistry/DMPK assays and their relation to the drug discovery process.
Ability to establish collaborative relationships with a range of people, both within and outside of the immediate team.
Able to manage own time effectively, adapt to regularly changing priorities, and to manage multiple activities simultaneously.
Anticipates potential problems and is proactive in taking action to avoid or minimise impact on service delivery.
Able to combine information from multiple sources in order to diagnose and solve problems.
Sets themselves challenging objectives, and demonstrates persistence in overcoming obstacles to achieve these.
Education, Qualifications and Experience
A minimum of a BSc or equivalent in a relevant area of life science, with at least 2 years’ experience working within a laboratory environment.
Direct experience in Physical Chemistry assays such as protein binding, aqueous solubility, lipophilicity or chemical stability is desirable.
Direct experience of working with automated liquid handling systems, liquid chromatography and mass spectroscopy instruments is preferred but not essential.
Computer literate with experience of using Microsoft Office
Rewards & Benefits:
Cyprotex aims to encourage, support and recognise the excellent performance and behaviour of our colleagues. Our performance-based compensation policy applies to all colleagues of the Evotec Group companies. We offer a variety of benefits and these include, amongst others, excellent pension benefits and service related holidays. We recognise that our colleagues have full lives away from the workplace and support working patterns that balance private life and career.
Career Development:
As part of the Evotec Group, we grow through innovation, collaboration, nurturing our people and continuing to develop as a world-class organisation.
Our work is challenging and requires the most competent staff, therefore we aim to recruit and retain the best. We look for talented individuals from all walks of life, educational backgrounds and nationalities to provide the expertise and dedication to enable us to continually achieve success in all that we do. We offer equal opportunities for people with or without, visible or not-visible disabilities.
If you are interested in this exciting opportunity please apply here.
Closing date for application is Friday 15th January 2021.
Cyprotex, part of the Evotec Group, are recruiting for a Study Manager / Associate Study Manager to join our Project Management team based at Watertown, MA.
It’s the caliber of our people that creates our success so we’re looking for a highly self-motivated Study Manager / Associate Study Manager (dependent on experience) to join our Project Management group. In this role, you will be working alongside our Project Managers, Heads of Function, Scientists, and Business Development Directors, with primary responsibility for managing client studies. The position is full time.
Primary Responsibilities:
Working in our Project Management Team, your responsibilities will include but are not limited to:
Ideal candidate profile:
Expertise & skills (not limited to):
Cyprotex, an Evotec company, is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, gender, age, disability, genetic information, gender expression, gender identity, national origin, religion, sexual orientation, or veteran status.
Cyprotex US, an Evotec company, specializes in ADME-Tox and Biosciences including both in vitro (laboratory experiments) and in silico (computer modelling) approaches. Cyprotex was founded in 1999. The Company serves the Pharmaceutical and Biotech, Cosmetics/Personal Care and Chemicals Industries as well as academia and not-for-profit organizations. Over 1700 organizations trust Cyprotex for their ADME-Tox and Bioscience research needs.
We are seeking a Senior Scientist and/or Scientist to be responsible for conducting routine ADME assays as well as participating in experimental design, performing experiments, troubleshooting, and performing data analysis and interpretation. This position is based on Watertown, Massachusetts.
Duties and Responsibilities
Qualifications:
Skills:
Cyprotex, an Evotec company, is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, gender, age, disability, genetic information, gender expression, gender identity, national origin, religion, sexual orientation, or veteran status.
Cyprotex US, an Evotec company, specializes in ADME-Tox and Biosciences including both in vitro (laboratory experiments) and in silico (computer modelling) approaches. Cyprotex was founded in 1999. The Company serves the Pharmaceutical and Biotech, Cosmetics/Personal Care and Chemicals Industries as well as academia and not-for-profit organizations. Over 1700 organizations trust Cyprotex for their ADME-Tox and Bioscience research needs.
We are seeking an ADME Scientist and/or Associate Scientist to join its ADME/DMPK group. This individual will work with scientists in the group to support our clients’ discovery and development of safe and effective medicines by elucidating the absorption, distribution, metabolism, excretion and pharmacokinetic properties of small molecule and peptide drug candidates.
This individual will perform a range of in vitro ADME assays (ex: solubility, microsomal stability, PPB, Cyp inhibition) and PK studies to support the discovery and development of small molecule and peptide therapeutics. In this lab-based position, the qualified candidate will work closely with our established team to develop and conduct ADME assays to address ADME questions and support projects. The successful candidate would have the opportunity to interact with multidisciplinary project teams.
Required Experience
This scientist position requires a bachelor’s degree (3-5 years experience) or Masters (0-3 years experience) in biology, chemistry, pharmaceutical sciences, or an equivalent combination of education, training and experience from which comparable knowledge, skills and abilities have been attained. The title will be commensurate with experience. Additionally, excellent writing and verbal communication skills that enable the candidate to function effectively on a collaborative multi-disciplinary work team. Very strong organization skills and attention to detail will be essential, especially for performing the in-vitro assays for this job.
Please apply at https://evotecgroup.wd3.myworkdayjobs.com/Evotec_Career_Site/job/Watertown-Cyprotex/Scientist-Associate-Scientist---ADME_REQ-02200-1
Preferred Experiences
* Detailed knowledge of bioanalysis within ADME/DMPK
* Hands on experience of bioanalytical method development and quantification of small molecules and peptides in complex matrices
* Strong understanding of UPLC-MS/MS systems
* Trouble-shooting skills in assays and instrumentation
* An understanding of pharmacokinetic parameter determination and interpretation
* Experience locating and applying information in the scientific literature
Cyprotex, an Evotec company, is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, gender, age, disability, genetic information, gender expression, gender identity, national origin, religion, sexual orientation, or veteran status.
Cyprotex, an Evotec company, specializes in ADME-Tox and Biosciences including both in vitro (laboratory experiments) and in silico (computer modelling) approaches. Cyprotex was founded in 1999. The Company serves the Pharmaceutical and Biotech, Cosmetics/Personal Care and Chemicals Industries as well as academia and not-for-profit organizations. Over 1700 organizations trust Cyprotex for their ADME-Tox and Bioscience research needs.
The team is looking for a highly motivated Associate Scientist or Scientist that will be responsible for routine screening of compounds in various in vitro toxicology assays.
Job Responsibilities
Qualifications
Evotec is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, gender, age, disability, genetic information, gender expression, gender identity, national origin, religion, sexual orientation, or veteran status.