Established in 1999, Cyprotex has over 150 staff based at its sites in the UK (Alderley Park in Cheshire) and in the USA (Watertown, MA). We operate as a contract research organisation and we have over 1700 customers worldwide within industries such as the pharmaceutical, cosmetics and personal care and the chemical and agrichemical markets. Outstanding customer service excellence and quality are key focuses of the business. In addition to our customer projects, we invest heavily in Research and Development of new techniques – many of these projects are exploring new in vitro or in silico methods to understand how chemicals or new pharmaceuticals may behave in humans in terms of their safety or efficacious effects.
Cyprotex is a growing and successful business and we are constantly recruiting for motivated and hardworking staff who thrive within a dynamic and vibrant organisation. We are committed to providing an environment where employees can learn and develop their skills and are recognised and rewarded for the contribution they make to the Company. Much of our work is performed in multi-disciplinary project teams that enables exchange of ideas and knowledge, enabling people to develop and take on additional responsibility either within the team or across teams in the business.
Watch our video to learn more about our UK facility at Alderley Park.
If you want to build your career with us, and contribute to our success, please send your CV to Human Resources.
Cheshire, UK
Cyprotex, part of the Evotec Group, are recruiting for a Software Engineer to join our Information Systems team based at Alderley Park, Cheshire, UK.
It’s the calibre of our people that creates our success so we’re looking for someone who loves to write good software, and has a willingness to help people. The software you design and deliver will help maintain existing systems and contribute to the development of new applications to support our experimental and predictive science and to enhance scientist throughput & productivity.
You will be working closely with Cyprotex scientists, gathering requirements and delivering solutions for software that they use daily. Our software is not only pivotal to the smooth working of our business but also through the clients and collaborators that we work with will also aid in identifying ground breaking drugs, helping to transform the lives of millions of patients, so you will be making a real difference.
Ideal candidate profile:
• Able to make a positive contribution to a team
• Establishes constructive and collaborative relationships with colleagues
• Experienced in overcoming obstacles and demonstrating resilience in their day to day work
• Demonstrates resourcefulness and purpose to deliver the best results
• Excellent attention to detail
• Proactively networks across teams in a timely way
• Is agile; able to work with conflicting priorities, and respond positively to changing demands
• Is able to define and interpret user requirements and translate them into system design & subsequent delivery
Essential skills: • Any OO language (Java, C#)
• Experience using build tools (e.g Ant, Maven, Gradle)
• Experience building RESTful services (JSON)
• Knowledge of continuous integration and unit testing
Desirable skills (not limited to): • Oracle SQL
• Python
• Type Script
• Experience with code reviews
Qualifications: • Minimum BSc in a relevant degree (e.g. computer science, bioinformatics, mathematics, physics).
Rewards & Benefits Cyprotex aims to encourage, support and recognise the excellent performance and behaviour of our colleagues. Our performance-based compensation policy applies to all colleagues of the Evotec Group companies. We offer a variety of benefits and these include, amongst others, excellent pension benefits and service related holidays. We recognise that our colleagues have full lives away from the workplace and support working patterns that balance private life and career.
Career Development As part of the Evotec Group, we grow through innovation, collaboration, nurturing our people and continuing to develop as a world-class organisation.
Our work is challenging and requires the most competent staff, therefore we aim to recruit and retain the best. We look for talented individuals from all walks of life, educational backgrounds and nationalities to provide the expertise and dedication to enable us to continually achieve success in all that we do. We offer equal opportunities for people with or without, visible or not-visible disabilities.
If you are keen to be a part of our successful and growing global business, please upload an up-to-date CV and covering letter to the Evotec website using the following link:
www.evotec.com The closing date for receipt of applications is 5pm on Friday, 9th November 2018. Applicants will need to be available for interview w/c 19th November 2018.
Direct applications only – no agencies please.
Due to internal promotions, Cyprotex, part of the Evotec Group, are recruiting for Associate Scientists to join our Drug Metabolism team based at Alderley Park, Cheshire, UK.
It’s the calibre of our people that creates our success so if you are a talented, driven and ambitious graduate with a scientific degree, you could become an integral member of our Drug Metabolism team.
As part of this team, you will work closely with other laboratory staff to ensure that experimental aspects of in vitro ADMET studies are performed to a high standard and within scheduled time frames. In return, we will provide you with the opportunity to absorb a mixture of first-rate technical training and invaluable experience to develop your scientific expertise.
Principal Accountabilities Support high and low throughput ADMET screening assays such as metabolic stability and CYP450 inhibition assays for commercial as well as research and development activities.
Perform work to a high quality, within specified timelines, and within safety regulations.
Assist in running and maintaining robotic systems to support high throughput ADMET processes.
Assist in data analysis and interpretation by applying knowledge of biochemistry and cell biology in ADMET processing.
Prepare compounds, stock solutions and buffers.
Routine calibration of laboratory equipment.
Experience Minimum of BSc in a life science subject preferably with experience of working within a laboratory environment (such as a placement year or extended research project). Direct experience in DMPK or ADMET assays or working with automated liquid-handling and robotics systems would also be advantageous.
Previous experience of laboratory processes and cell culture techniques would be desirable. Knowledge of HPLC, LC-MS or LC-MS/MS advantageous but not essential.
Skills & Competencies Highly self-motivated and personable.
Able to communicate effectively within a team environment.
Able to organise daily tasks, to frequently work under pressure and to meet tight deadlines.
Possess meticulous attention to detail, performing work to an exceptionally high standard, and within company and statutory safety regulations.
Able to use initiative to solve problems and troubleshoot with the assistance of other members of the team.
Should be computer literate with previous experience using Microsoft Office.
Rewards & Benefits Cyprotex aims to encourage, support and recognise the excellent performance and behaviour of our colleagues. Our performance-based compensation policy applies to all colleagues of the Evotec Group companies. We offer a variety of benefits and these include, amongst others, excellent pension benefits and service related holidays. We recognise that our colleagues have full lives away from the workplace and support working patterns that balance private life and career.
Career Development As part of the Evotec Group, we grow through innovation, collaboration, nurturing our people and continuing to develop as a world-class organisation.
Our work is challenging and requires the most competent staff, therefore we aim to recruit and retain the best. We look for talented individuals from all walks of life, educational backgrounds and nationalities to provide the expertise and dedication to enable us to continually achieve success in all that we do. We offer equal opportunities for people with or without, visible or not-visible disabilities.
If you are keen to be a part of our successful and growing global business, please upload your current CV and covering letter to the evotec website via the following link:
www.evotec.com The closing date for receipt of applications is 5pm on Monday, 19th November 2018. Interviews will take place on Wednesday, 28th November and Wednesday, 5th December 2018.
Direct applications only - no agencies please.
Industrial Placement Students
What better way to kick start your career in the Science Industry in July 2019 than with a 12-month placement at Cyprotex!
We are currently seeking applications for our Industrial Placement Programme with opportunities in our Scientific, Analytical and Information Systems (IS) departments based at Alderley Park in Cheshire. Our Scientific and Analytical departments are at the heart of Cyprotex’s business and are at the forefront of new science and technology as well as delivering high-quality results to our clients combined with excellent customer service, while our IS department is responsible for building and maintaining our integral in-house software system for managing our scientific workflows and result delivery.
To gain access to our programmes, you will need to be studying either Biology, Chemistry, Computer Science or a similar discipline at undergraduate level.
As a Placement Student within the Science Department you will work within one of our ADME, Toxicology or Analytical Teams. You will have a passion for laboratory science, data analysis and scientific technology and will be responsible for performing experiments for our clients in collaboration with other scientific staff. As a Placement Student within the IS Department you will be working alongside our Software Engineers and Data Scientists who are responsible for supporting our scientific staff to deliver their data through development of innovative software systems.
As a Science Student you will gain experience of working on customer projects in a fast-paced, delivery-focused scientific environment. This includes:
• Supporting our customer projects by conducting scientific experiments with defined, agreed objectives and timelines.
• Contributing to the design, execution and interpretation of experiments with help from other team members.
• Adapting scientific knowledge to resolve research problems encountered in achieving defined goals with assistance from line manager or other team members to meet internal and client-driven deadlines.
• Preparing reports of findings, presenting data, and collaborating with other colleagues at Cyprotex.
• Presenting your own work at technical meetings when required.
As an IS Software Student you will gain experience of working on customer projects in an agile, fast-paced, delivery-focused scientific environment. This includes:
• Designing and implementing new systems using suitable modern programming languages including Java, python and .Net.
• Participating in the adoption of software development best practices within the IS team, including code review, documentation and unit testing.
• Interacting with scientists to gather software requirements.
• Positively contributing updates, ideas and solutions in team meetings.
Please note these placements are ideally suited to those students looking to gain experience of working in industry. You will be allocated an individual mentor who will support your personal development throughout the placement.
If you are excited by this opportunity to join our world class science business and would like to apply for a placement, please upload your up-to-date CV and covering letter to the evotec website using the following link:
www.evotec.com
The closing date for all applications is 5pm on Friday, 30 November 2018.
We will be holding our assessment centres on Thursday 3rd and Friday 4th January 2019. These paid placements are always popular, so please don’t hesitate to take the opportunity to submit your application as soon as possible.
Direct applications only – no agencies please.
TOXICOLOGY OPPORTUNITIES – SCIENTIST/SENIOR RESEARCH SCIENTIST Cyprotex, part of the Evotec Group, are recruiting for experienced talent, ranging from Scientist to Senior Research Scientist, to join our in vitro Toxicology Group based at Alderley Park, Cheshire, UK.
It’s the calibre of our people that creates our success and these roles would be ideal for individuals with experience in one or more of the responsibilities/techniques listed below with particular interest in a lab-based role within a fast-paced commercial environment.
You would be working closely with other laboratory staff to ensure that experimental aspects of in vitro toxicity studies are performed to a high standard and within scheduled time frames.
Principal Accountabilities Support high and low throughput Toxicology screening processes for commercial as well as research and development activities.
Perform work to a high quality, within specified timelines, and within safety regulations.
Assist in running and maintaining robotic systems to support high throughput Toxicology processes.
Assist in data analysis and interpretation.
Responsibilities Run routine in vitro Toxicology assays in a variety of cell lines using techniques/instruments such as High Content Imaging (HCI), flow cytometry and Seahorse
Cell culture in both 2D and 3D formats
Data analysis and reporting
Assay development, contributing to R&D and improvement projects and troubleshooting
Laboratory support including ordering, equipment calibration and validation Working to a high standard and adhering to our Quality System.
Contributing to our Quality System via preparation of SOP’s
Interacting with our Information Systems Team to drive automation and data processing tools Training of more junior team members
Ensuring high standards of data quality and productivity within the team
Work closely with the Project Managers to ensure the requirements of our clients are met
Keeping up to date with scientific advances
Experience Minimum of BSc in a life science subject preferably with experience of working within a laboratory environment (such as a placement year or extended research project). For senior positions 3+ years’ experience in industry or post-doctoral experience.
Cell culture experience is essential, with routine maintenance of adherent cell lines.
Direct experience in cell imaging, cell based toxicology assays such as cell viability assays is advantageous.
Knowledge of high content imaging (HCI), plate based assays and flow cytometry is also advantageous but not essential.
Skills & Competencies Highly self-motivated and personable.
Able to communicate effectively within a team environment.
Able to organise daily tasks, to frequently work under pressure and to meet tight deadlines.
Possess excellent attention to detail, performing work to an exceptionally high standard.
Able to use initiative to solve problems and troubleshoot with the assistance of other members of the team.
Should be computer literate with previous experience using Microsoft Office.
Rewards & Benefits Cyprotex aims to encourage, support and recognise the excellent performance and behaviour of our colleagues. Our performance-based compensation policy applies to all colleagues of the Evotec Group companies. We offer a variety of benefits and these include, amongst others, excellent pension benefits and service related holidays. We recognise that our colleagues have full lives away from the workplace and support working patterns that balance private life and career.
Career Development As part of the Evotec Group, we grow through innovation, collaboration, nurturing our people and continuing to develop as a world-class organisation. Our work is challenging and requires the most competent staff, therefore we aim to recruit and retain the best. We look for talented individuals from all walks of life, educational backgrounds and nationalities to provide the expertise and dedication to enable us to continually achieve success in all that we do. We offer equal opportunities for people with or without, visible or not-visible disabilities.
If you are keen to be a part of our successful and growing global business, please upload an up-to-date CV and covering letter to the evotec website via the following link:
www.evotec.comThe closing date for receipt of applications is 5pm on Friday, 16th November 2018. Applicants will need to be available for interview w/c 26th November 2018.
Direct applications only - no agencies please.
Watertown, MA, USA
Job description
This is an opportunity for recent graduates seeking entry into the biotechnology industry to gain hands-on in vitro ADME-TOX and mass spectrometry experience with a world leader in ADMET innovation.
Cyprotex US, LLC is expanding and seeking hands-on, highly motivated scientists at multiple levels to conduct ADME-Tox assays independently. The successful candidate will actively participate in experimental design, performing experiments, and troubleshooting, as well as performing data analysis and interpretation. The ideal candidate will be independent, self-motivated, collaborative and able to multitask effectively while frequently under pressure to meet tight deadlines.
Requirements
• Excellent interpersonal skills, communication skills, and work ethic.
• Excellent organization, documentation and communication skills
• Degree in Pharmacy, Chemistry, Biochemistry, Physics, or Engineering with a strong desire to learn a drug metabolism and toxicology skillset
• Ability to interpret results, identify issues, troubleshoot and propose solutions to study design, execution, analysis and interpretation
• Knowledge of current regulatory guidance relating to ADME-TOX a plus Basic Qualifications
• Results-oriented B.S./M.S./PhD-level scientist with a strong science background
• Biotechnology/Pharmaceutical career orientation Preferred Qualifications
• Experience testing compounds in cell based or biochemical assays
• Use of analytical equipment such as HPLC and (u)HPLC-MS/MS
• Experience with laboratory automation systems, including liquid handling systems.
Principals only. Candidates must currently possess unrestricted authorization to work in the United States. At this time, the company does not intend to sponsor work visas for this position.
Job Type: Full-time
Required education:
• Bachelor's, Master’s, or PhD
To apply, email your résumé to US-careers@cyprotex.com
Cyprotex US is looking for an Associate Scientist based in Watertown, MA to assume responsiblity for the routine screening of compounds in various in vitro toxicology assays and reporting to the Associate Director or Senior Scientist. There will be no direct reports.
PRINCIPAL ACCOUNTABILITES
- Cell Culture experience with immortalized cell lines. (Primary cell experience a plus).
- Responsible for planning and conducting high and low throughput toxicology screens, processing data to a high quality of standards, and within specified time frames.
- To assist the Scientist with validation and investigative assays.
- To monitor and maintain stock consumables where required.
- To help with the validation and routine maintenance of laboratory equipment.
- To provide support to the Senior Scientist, Laboratory Supervisors and Senior Research Scientist when trouble shooting.
- Identifies, within their group, where support is required and manages their own time sufficiently to provide this support.
- To follow safety regulations and quality control procedures.
- To report any issues of concern and discuss/advise scientific strategy with the Laboratory Supervisor and/or Senior Research Scientist.
- To be aware of the Cyprotex Quality Policy and procedures and to work within the terms of the Cyprotex Quality policy.
- To periodically contribute to the writing and review of SOPs and to keeping them up to date.
LIKELY CHARACTERISICS
- The incumbent is likely holding a BS or equivalent experience in a relevant bio scientific discipline with at least 1-2 years experience working within industry (pharma or CRO).
- Effective communication and organizational skills, and the ability to troubleshoot and multitask under pressure of deadlines are important.
To apply, email your résumé to US-careers@cyprotex.com
This is an opportunity for a scientist with hands-on in vitro ADME experience to join a fast-paced international company, the world leader in ADMET innovation.
Cyprotex US, LLC is seeking a hands-on, highly motivated scientist to conduct routine ADME assays independently. The successful candidate will actively participate in experimental design, performing experiments, and troubleshooting, as well as performing data analysis and interpretation. The ideal candidate will be independent, self-motivated, collaborative and able to multitask effectively while frequently under pressure to meet tight deadlines.
Requirements
• Have performed routine in vitro ADME assays in the past, preferably in a CRO or pharmaceutical company
• Excellent organization, documentation and communication skills
• Broad knowledge of pharmaceutical DMPK/ADME or related disciplines
• Ability to interpret results, identify issues, troubleshoot and propose solutions to study design, execution, analysis and interpretation
• Knowledge of current regulatory guidance relating to ADME
Basic Qualifications
• Results-oriented B.S./M.S.-level scientist with a biological science background
• A minimum of 2 years of relevant, hands-on industry experience focused on ADME assays
Preferred Qualifications
• Experience testing compounds in cell based or biochemical assays
•Use of analytical equipment such as HPLC and (u)HPLC-MS/MS
• Experience with laboratory automation systems, including liquid handling systems.
Principals only. Candidates must currently possess unrestricted authorization to work in the United States. At this time, the company does not intend to sponsor work visas for this position.
Job Type
Permanent
Required Education
Bachelor's
Required Experience
ADME/DMPK: 2 years
To apply, email your résumé to US-careers@cyprotex.com
Evotec Group
Visit the Evotec website to see the current vacancies
https://recruitment.evotec.com/Vacancy.aspx
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