Careers

Salary: Competitive
Location: Alderley Park
Level: Technical
Hours: 37.5 per week/5 days
Benefits: Standard

Cyprotex, part of the Evotec Group, are recruiting for a Study Manager to join our Project Management team based at Alderley Park, Cheshire, UK. We are looking for a highly self-motivated individual specialising in in vitro Toxicology. In this role you will be working alongside our Head of Toxicology and Project Managers, with primary responsibility for managing client studies.

Working in our Project Management Team, your responsibilities will include but are not limited to:
• Managing client studies to a high standard, ensuring all information is communicated effectively to laboratory staff, client requirements are followed and data is returned within specified deadlines.
• Ensuring tracking systems are up to date with respect to ongoing client work. • With support from business development colleagues and Principal Scientists, to prepare pricing, proposals and work orders where appropriate.
• Liaising with external customers to co-ordinate transfer of information and compounds between customer and Cyprotex.
• Providing the customer with advice and data interpretation, drawing on own expertise and that of internal network.
• Maintaining, and developing relationships with existing clients, tracking revenues trends/discounts and identifying new opportunities for growth within existing opportunities.
• Managing/performing internal R&D projects (~20% of time).

Ideal candidate profile:
• Able to make a positive contribution to a team
• Establishes constructive and collaborative relationships with colleagues
• Experienced in overcoming obstacles and demonstrating persistence in their day to day work
• Demonstrates resourcefulness and purpose to deliver the best results
• Excellent attention to detail; records information accurately
• Proactively networks across teams in a timely way
• Is agile; able to work with conflicting priorities, and respond positively to changing demands

Expertise & skills (not limited to):
• A degree in a Toxicology related science, or relevant experience accordingly. • A minimum of 3 years’ experience in either pharmaceutical/biotech industries and/or related contract research services.

As part of the Evotec Group, we grow through innovation, collaboration, nurturing our people and continuing to develop as a world-class organisation.

Our work is challenging and requires the most competent staff, therefore we aim to recruit and retain the best. We look for talented individuals from all walks of life, educational backgrounds and nationalities to provide the expertise and dedication to enable us to continually achieve success in all that we do. We offer equal opportunities for people with or without, visible or not-visible disabilities.

In return we offer excellent training and benefits, including a highly competitive salary package and pension scheme. If you are keen to be a part of our successful and growing global business, please send an up-to-date CV and covering letter to recruiting@cyprotex.com. The closing date for receipt of applications is midday on Friday, 28th September 2018. Applicants will need to be available for interview w/c 8th October 2018.

Position Information:
Cyprotex, part of the Evotec Group, are recruiting a Senior Research Scientist to join our Analytical Team based at Alderley Park, Cheshire, UK.

We are seeking an individual with extensive analytical experience ideally obtained within a discovery or bioanalytical environment either as a post-graduate or from working within the industry. A minimum of a BSc in a relevant field as well as hands-on experience of maintaining and using LC-MS/MS systems (Triple quadrupole and High resolution) in support of small and large molecule bioanalysis projects are required.

Primary Responsibilities:
The primary responsibilities include but are not limited to:

• Development of customised LC-MS/MS methods for analysis of potentially challenging compounds in a range of biological matrices including utilisation of reverse phase and Hilic chromatography
• Troubleshooting and system maintenance and co-ordination of engineer visits MS/MS and UPLC process optimisation for high volumes of compounds using automated tools and established processes
• Leading training of more junior team members and contributing to scientific knowledge sharing.
• Contributing to our Quality System via preparation and review of SOPs Collaborating effectively with our Information Systems Team to design and implement automation and data processing tools. Seeking opportunities to form additional collaborative relationships
• Promote and support a continuous improvement culture

Additional Responsibilities may include:

• Line management including personal development of direct reports
• Scheduling of lab activities and resources for bespoke bioanalytical activities Flexing into other analytical areas to provide resource/cover given suitable training and supervision
• Working with assay scientists to maximise quality and throughput

Knowledge, Skills and Abilities
Essential:

• Hands-on experience of utilising LC-MS/MS techniques for analysis of small and large molecules in preclinical samples from within a discovery, development or CRO setting 
• The ability to perform routine maintenance on LC-MS/MS equipment
• A high level of attention to detail and well organised with an ability to work without close supervision
• Ability to adapt to changing priorities, manage multiple activities simultaneously and to achieve timelines
• Motivational team player with a high level of dedication
• Extensive computer literacy including use of Microsoft Office
• Ability to rapidly learn new techniques and processes

Preferred but not essential:

• Advanced LC-MS/MS maintenance skills
• Experience with MassLynx™, Analyst™ or other Mass Spectrometry data acquisition software packages
• A wider knowledge of analytical support in drug discovery/development (e.g bioanalytical method validation)
• A knowledge of DMPK/ADME assays within drug discovery/development

Qualifications

• Minimum BSc in relevant scientific discipline covering chemistry

As part of the Evotec Group, we grow through innovation, collaboration, nurturing our people and continuing to develop as a world-class organisation.

Our work is challenging and requires the most competent staff, therefore we aim to recruit and retain the best. We look for talented individuals from all walks of life, educational backgrounds and nationalities to provide the expertise and dedication to enable us to continually achieve success in all that we do. We offer equal opportunities for people with or without, visible or not-visible disabilities.

In return we offer excellent training and benefits, including a highly competitive salary package and pension scheme. If you are keen to be a part of our successful and growing global business, please send an up-to-date CV and covering letter to recruiting@cyprotex.com. The closing date for receipt of applications is Monday, 10^th September 2018.

Job description

This is an opportunity for recent graduates seeking entry into the biotechnology industry to gain hands-on in vitro ADME-TOX and mass spectrometry experience with a world leader in ADMET innovation.

Cyprotex US, LLC is expanding and seeking hands-on, highly motivated scientists at multiple levels to conduct ADME-Tox assays independently. The successful candidate will actively participate in experimental design, performing experiments, and troubleshooting, as well as performing data analysis and interpretation. The ideal candidate will be independent, self-motivated, collaborative and able to multitask effectively while frequently under pressure to meet tight deadlines.

Requirements
• Excellent interpersonal skills, communication skills, and work ethic.
• Excellent organization, documentation and communication skills
• Degree in Pharmacy, Chemistry, Biochemistry, Physics, or Engineering with a strong desire to learn a drug metabolism and toxicology skillset
• Ability to interpret results, identify issues, troubleshoot and propose solutions to study design, execution, analysis and interpretation
• Knowledge of current regulatory guidance relating to ADME-TOX a plus Basic Qualifications
• Results-oriented B.S./M.S./PhD-level scientist with a strong science background
• Biotechnology/Pharmaceutical career orientation Preferred Qualifications
• Experience testing compounds in cell based or biochemical assays
• Use of analytical equipment such as HPLC and (u)HPLC-MS/MS
• Experience with laboratory automation systems, including liquid handling systems.

Principals only. Candidates must currently possess unrestricted authorization to work in the United States. At this time, the company does not intend to sponsor work visas for this position.

Job Type: Full-time

Required education:
• Bachelor's, Master’s, or PhD

To apply, email your résumé to US-careers@cyprotex.com

Cyprotex US is looking for an Associate Scientist based in Watertown, MA to assume responsiblity for the routine screening of compounds in various in vitro toxicology assays and reporting to the Associate Director or Senior Scientist.  There will be no direct reports.

PRINCIPAL ACCOUNTABILITES

• Cell Culture experience with immortalized cell lines. (Primary cell experience a plus).
• Responsible for planning and conducting high and low throughput toxicology screens, processing data to a high quality of standards, and within specified time frames.
• To assist the Scientist with validation and investigative assays.
• To monitor and maintain stock consumables where required.
• To help with the validation and routine maintenance of laboratory equipment.
• To provide support to the Senior Scientist, Laboratory Supervisors and Senior Research Scientist when trouble shooting.
• Identifies, within their group, where support is required and manages their own time sufficiently to provide this support.
• To follow safety regulations and quality control procedures.
• To report any issues of concern and discuss/advise scientific strategy with the Laboratory Supervisor and/or Senior Research Scientist.
• To be aware of the Cyprotex Quality Policy and procedures and to work within the terms of the Cyprotex Quality policy.
• To periodically contribute to the writing and review of SOPs and to keeping them up to date.

LIKELY CHARACTERISICS

• The incumbent is likely holding a BS or equivalent experience in a relevant bio scientific discipline with at least 1-2 years experience working within industry (pharma or CRO).
• Effective communication and organizational skills, and the ability to troubleshoot and multitask under pressure of deadlines are important.

To apply, email your résumé to US-careers@cyprotex.com

This is an opportunity for a scientist with hands-on in vitro ADME experience to join a fast-paced international company, the world leader in ADMET innovation.

Cyprotex US, LLC is seeking a hands-on, highly motivated scientist to conduct routine ADME assays independently. The successful candidate will actively participate in experimental design, performing experiments, and troubleshooting, as well as performing data analysis and interpretation. The ideal candidate will be independent, self-motivated, collaborative and able to multitask effectively while frequently under pressure to meet tight deadlines.

Requirements

• Have performed routine in vitro ADME assays in the past, preferably in a CRO or pharmaceutical company

• Excellent organization, documentation and communication skills

• Broad knowledge of pharmaceutical DMPK/ADME or related disciplines

• Ability to interpret results, identify issues, troubleshoot and propose solutions to study design, execution, analysis and interpretation

• Knowledge of current regulatory guidance relating to ADME

Basic Qualifications

• Results-oriented B.S./M.S.-level scientist with a biological science background

• A minimum of 2 years of relevant, hands-on industry experience focused on ADME assays

Preferred Qualifications

• Experience testing compounds in cell based or biochemical assays

•Use of analytical equipment such as HPLC and (u)HPLC-MS/MS

• Experience with laboratory automation systems, including liquid handling systems.

Principals only. Candidates must currently possess unrestricted authorization to work in the United States. At this time, the company does not intend to sponsor work visas for this position.

Job Type

Permanent

Required Education

Bachelor's

Required Experience

ADME/DMPK: 2 years

To apply, email your résumé to US-careers@cyprotex.com

Visit the Evotec website to see the current vacancies

https://recruitment.evotec.com/Vacancy.aspx