Careers

Cyprotex, part of the Evotec group are recruiting a Senior Research Scientist to join our Bioanalytical Team based at Alderley Park, Cheshire, UK. The Bioanalytical team supports in vivo discovery pk studies, bioanalytical discovery projects and bespoke method development activities.

We are seeking an individual with extensive analytical experience ideally obtained within a discovery or bioanalytical environment either as a post-graduate or from working within the industry. A minimum of a BSc in a relevant field as well as hands-on experience of maintaining and using LC-MS/MS systems (Triple quadrupole and High resolution) in support of small and large molecule bioanalysis projects are required.

Primary Responsibilities:
The primary responsibilities include but are not limited to:

• Development of customised LC-MS/MS methods for analysis of potentially challenging compounds in a range of biological matrices including utilisation of reverse phase and Hilic chromatography
• Troubleshooting and system maintenance and co-ordination of engineer visits MS/MS and UPLC process optimisation for compounds using automated tools and established processes
• Leading training of more junior team members and contributing to scientific knowledge sharing.
• Contributing to our Quality System via preparation and review of SOPs Collaborating effectively with our Information Systems Team to design and implement automation and data processing tools.
• Seeking opportunities to form additional collaborative relationships
• Promote and support a continuous improvement culture

Additional Responsibilities may include:

• Line management including personal development of direct reports
• Scheduling of lab activities and resources for bespoke bioanalytical activities Flexing into other analytical areas to provide resource/cover given suitable training and supervision
• Working with assay scientists to maximise quality and throughput Knowledge,

Skills and Abilities Essential:

• Hands-on experience of utilising LC-MS/MS techniques for analysis of small and large molecules in preclinical samples from within a discovery, development or CRO setting
• Proven record of accomplishment in bioanalytical method development including good knowledge of MS, chromatography and sample preparation techniques.
• The ability to perform routine maintenance on LC-MS/MS equipment
• A high level of attention to detail and well organised with an ability to work without close supervision
• Ability to adapt to changing priorities, manage multiple activities simultaneously and to achieve timelines
• Motivational team player with a high level of dedication
• Extensive computer literacy including use of Microsoft Office Ability to rapidly learn new techniques and processes

Preferred but not essential

• Advanced LC-MS/MS maintenance skills. Experience with MassLynx™, Analyst™ or other Mass Spectrometry data acquisition software packages.
• A wider knowledge of analytical support in drug discovery/development (e.g bioanalytical method validation)
• A knowledge of DMPK/ADME assays within drug discovery/development

Qualifications
Minimum BSc in relevant scientific discipline covering chemistry.

Rewards and Benefits
Cyprotex aims to encourage, support and recognise the excellent performance and behaviour of our colleagues. Our performance-based compensation policy applies to all colleagues of the Evotec Group companies. We offer a variety of benefits, which include amongst others, excellent pension benefits and service related holidays. We recognise that our colleagues have full lives away from the workplace and support working patterns that balance private life and career.

Career Development
As part of the Evotec Group, we grow through innovation, collaboration, nurturing our people and continuing to develop as a world-class organisation.

We aim to recruit and retain the best because our work is challenging and requires the most competent staff. We look for talented individuals from all walks-of life, educational backgrounds and nationalities, to provide the expertise and dedication to enable us to achieve continual success in everything we do. We offer equal opportunities for people with or without, visible or not-visible disabilities.

If you are keen to be a part of our successful and growing global business, please upload an up-to-date CV and covering letter via the website using the following link:

Please submit your application here

The closing date for receipt of applications is 5pm on Friday, 26th July 2019. Applicants will need to be available for interview w/c 5th August 2019.

Direct applications only – no agencies please.

Cyprotex, part of the Evotec Group, are recruiting for experienced talent, at Scientist/Senior Scientist level, to join our Drug Metabolism team based at Alderley Park, Cheshire, UK.

It’s the calibre of our people that creates our success and this role would be ideal for an individual with drug metabolism experience, to work in a lab-based role within a fast-paced commercial environment.

As an integral member of the Drug Metabolism team you will work closely with other laboratory staff to ensure that experimental aspects of in vitro drug metabolism studies are performed to a high standard and within scheduled time frames. Dependent on experience you may also be responsible for efficiently and effectively planning and managing people, equipment and assays to meet client demand.

Principal Accountabilities
Primary responsibilities include, but are not limited to:
• Supporting high and low throughput in vitro drug metabolism studies eg metabolic stability, reaction phenotyping, enzyme inhibition and enzyme induction assays, for commercial as well as research and development activities.
• Planning and conducting both routine and bespoke ADME assays to a high standard and within specified timelines.
• Supporting assay development and validation.
• Proactively looking for improvement opportunities within the group’s processes and assays
• Coaching and mentoring other members of the team.

Experience
Applicants will have a BSc in the life science field with at least 2 years’ experience working within a laboratory environment with relevant experience in biochemical assays. Direct experience of ADME assays such as metabolic stability, Cytochrome P450 inhibition, Cytochrome P450 induction is highly desirable. Strong knowledge of general laboratory processes is essential and experience of automated liquid handling systems, such as Tecan Evo platform, or LC-MS/MS analysis would be advantageous. Dependent on the role additional line management, supervising or mentoring experience is beneficial.

Skills & Competencies
• Highly self-motivated and personable.
• Able to communicate effectively within a team environment.
• Able to organise daily tasks, to work under pressure and to meet tight deadlines.
• Possess excellent attention to detail, performing work to an exceptionally high standard, and within company and statutory safety regulations.
• Able to use initiative to solve problems and troubleshoot
• Comfortable with adapting to changing work priorities.
• Should be computer literate with previous experience using Microsoft Office.   Development Opportunities
• To gain a sound understanding of the theory behind a broad range of in vitro drug metabolism assays including assay design and validation.
• To understand the application of in vitro drug metabolism results, and ADMET data in general, to early drug discovery and development.
• To work in a highly motivated, dynamic commercial environment.

Rewards & Benefits
Cyprotex aims to encourage, support and recognise the excellent performance and behaviour of our colleagues. Our performance-based compensation policy applies to all colleagues of the Evotec Group companies. We offer a variety of benefits and these include, amongst others, excellent pension benefits and service related holidays. We recognise that our colleagues have full lives away from the workplace and support working patterns that balance private life and career.

Career Development
As part of the Evotec Group, we grow through innovation, collaboration, nurturing our people and continuing to develop as a world-class organisation.

Our work is challenging and requires the most competent staff, therefore we aim to recruit and retain the best. We look for talented individuals from all walks of life, educational backgrounds and nationalities to provide the expertise and dedication to enable us to continually achieve success in all that we do. We offer equal opportunities for people with or without, visible or not-visible disabilities.

If you are keen to be a part of our successful and growing global business, please use the following link to upload your up-to-date CV and covering letter 

Submit your application here

The closing date is 2nd August 2019

• Please note that we will interview suitable candidates as they apply, so please don’t hesitate to take the opportunity to submit your application as soon as possible.

Cyprotex, part of the Evotec group are recruiting a Senior Scientist to join our Analytical Team based at Alderley Park, Cheshire, UK.

We are seeking an individual with analytical experience to work on Metabolite Identification studies. Analytical experience should ideally have been obtained within a discovery or bioanalytical environment either as a post-graduate or from working within the industry. A minimum of a BSc in a relevant field is required. Hands-on experience of maintaining and using LC-MS/MS systems in support of small molecule Metabolite Identification projects is desirable.

Primary Responsibilities:
The primary responsibilities include but are not limited to:
• Development of customised LC-MS/MS methods to support Metabolite ID studies.
• Troubleshooting and system maintenance and co-ordination of engineer visits.
• Running the analytical phase of Metabolite ID studies with involvement in high-resolution MS/MS analysis, structural elucidation and reporting.
• Setup and running of reactive metabolite assays including analysis and reporting.
• Contributing to our Quality System via preparation and review of SOPs.
• Collaborating effectively with our Information Systems Team to implement data processing tools. Seeking opportunities to form additional collaborative relationships.
• Promote and support a continuous improvement culture.

Additional Responsibilities may include:
• Contributing to the scheduling of lab activities and resources.
• Flexing into other analytical areas to provide resource/cover given suitable training and supervision.
• Working with assay scientists to maximise quality and throughput. Knowledge,

Skills and Abilities Essential:
• Experience of performing metabolite identification studies including structural elucidations based on LC-MS/MS data interpretation.
• Hands-on experience of utilising LC-MS/MS techniques for analysis of small and large molecules in invitro and invivo samples from within a discovery, development or CRO setting.
• The ability to perform troubleshooting and routine maintenance on LC-MS/MS equipment.
• A high level of attention to detail and well organised with an ability to work without close supervision.
• Ability to adapt to changing priorities, manage multiple activities simultaneously and to achieve timelines.
• Motivational team player with a high level of dedication.
• Extensive computer literacy including use of Microsoft Office.
• Ability to learn new techniques and processes at a fast pace.

Preferred but not essential
• Knowledge of invitro and in-vivo ADME assays used for metabolite profiling together with an understanding of compound structural changes that result in phase 1 and 2 metabolites formed in these assays.
• Advanced LC-MS/MS maintenance skills.
• Experience or knowledge of radiolabelled metabolite identification studies
• Experience with MassLynx™, Analyst™ or other Mass Spectrometry data-acquisition software packages.
• Experience of metabolite profiling software e.g. Metabolynx, Metabolite Pilot, Metasense
• A wider knowledge of analytical support in drug discovery/development (e.g. bioanalytical method validation).
• A knowledge of DMPK/ADME assays within drug discovery/development.

Qualifications
• Minimum BSc in relevant scientific discipline covering chemistry.

Rewards and Benefits
Cyprotex aims to encourage, support and recognise the excellent performance and behaviour of our colleagues. Our performance-based compensation policy applies to all colleagues of the Evotec Group companies. We offer a variety of benefits, which include amongst others, excellent pension benefits and service related holidays. We recognise that our colleagues have full lives away from the workplace and support working patterns that balance private life and career.

Career Development
As part of the Evotec Group, we grow through innovation, collaboration, nurturing our people and continuing to develop as a world-class organisation.

We aim to recruit and retain the best because our work is challenging and requires the most competent staff. We look for talented individuals from all walks-of life, educational backgrounds and nationalities, to provide the expertise and dedication to enable us to achieve continual success in everything we do. We offer equal opportunities for people with or without, visible or not-visible disabilities.

If you are keen to be a part of our successful and growing global business, please upload your current CV and a covering letter via the website, using the following link:

Submit your application here 

The closing date for receipt of applications is 5pm on Friday, 26th July 2019. Applicants will need to be available for interview w/c 5th August 2019.

Direct applications only – no agencies please.

Cyprotex, part of the Evotec Group, are looking to appoint a Junior Buyer to join our enterprising Procurement Team. This exciting opportunity will be based at Alderley Park in Cheshire and will report to the Procurement Manager based in Oxfordshire.

It’s the calibre of our people that creates our success and this role would be ideal for an experienced individual who thrives in a fast-paced commercial environment. The successful candidate will provide full procurement support to our Alderley Park based colleagues. To do this to a high standard, they will be able to demonstrate independence, initiative and collaboration and possess the passion and drive to work in an agile business.

Responsibilities include:
Order management and backup for procurement on pricing and invoicing process, resolving operational day-to-day supplier related subjects Identify and analyse potential cost savings
Negotiate Capex Purchases and Opex Contracts
Actively support procurement projects especially in E-Procurement and Lean initiatives
Maintain data in the ERP-system, content on catalogues and supplier management
Assist in the budgeting process of Capital Expenditure, support procurement process
Provide support to the Procurement Manager as required

Skills & Competencies -
Our Ideal Candidate Successfully completed BA/BSc degree in Economics or a similar subject Min 2-3 years purchasing experience High degree of self-motivation, reliability and flexibility Good negotiation experience with demonstrable savings
Proficiency in MS Office (Excel, PowerPoint, Word) and of ERP-programs Experience with E-Procurement/ electronic supplier catalogue management Strong numerical and analytical skills
Ability to assess problems and resolve or escalate to appropriate team members to resolve
Strong interpersonal skills with the ability to work and collaborate with others Excellent communication skills

Rewards & Benefits
Cyprotex aims to encourage, support and recognise the excellent performance and behaviour of our colleagues. Our performance-based compensation policy applies to all colleagues of the Evotec Group companies. We offer a variety of benefits and these include, amongst others, excellent pension benefits and service related holidays. We recognise that our colleagues have full lives away from the workplace and support working patterns that balance private life and career.

Broader Career Development
As part of the Evotec Group, we grow through innovation, collaboration, nurturing our people and continuing to develop as a world-class organisation.

Our work is challenging and requires the most competent staff, therefore we aim to recruit and retain the best. We look for talented individuals from all walks of life, educational backgrounds and nationalities to provide the expertise and dedication to enable us to continually achieve success in all that we do. We offer equal opportunities for people with or without, visible or not-visible disabilities.

If you are keen to be a part of our successful and growing global business, please upload an up-to-date CV and covering letter to the website using the following link:

Submit your application here

Cyprotex, part of the Evotec Group, are looking to appoint a Senior Research Scientist to join our in vitro Toxicology Group based at Alderley Park, Cheshire, UK.

It is the calibre of our people that creates our success and this role would be ideal for an experienced and innovative individual who thrives in a fast-paced commercial environment.

You would be working closely with other members of the team to ensure that in vitro toxicity studies, both commercial and R&D-based, are performed to a high standard and within scheduled time frames.

Principal Accountabilities

• Run high- and low-throughput in vitro Toxicology assays for commercial as well as research and development activities.
• Define and lead assay development, contributing to R&D and improvement projects and troubleshooting of assays in conjunction with the Team Leader. Perform data analysis and interpretation, supporting clients or Study Managers with advice when necessary.
• Perform work to a high standard, within specified timelines, and within safety regulations.

Responsibilities

• Running of routine in vitro Toxicology assays in a variety of cell lines using techniques/instruments such as High Content Imaging (HCI), flow cytometry and Seahorse.
• Cell culture in both 2D and 3D formats.
• Assist in running and maintaining robotic systems to support high throughput Toxicology processes.
• Keeping up to date with relevant scientific advances and regulatory guidelines in the field of in vitro toxicology.
• Adhering to our Quality System and contributing to further development of our Quality System via preparation and review of SOP’s.
• Interacting with our Information Systems Team to drive automation and data processing tools.
• Training of more junior team members and ensuring productivity of the team. Working closely with the Study Managers to ensure the requirements of our clients are met.

Experience

• Minimum of BSc in a life science subject with experience of working within a laboratory environment in industry or via post-doctoral experience.
• Cell culture experience is essential, with routine maintenance of adherent cell lines.
• Experience in experimental performance, data processing and result interpretation, ideally with experience of High Content Screening (HCS), cytotoxicity assays and/or flow cytometry.
• Previous employment within a contract research environment would be desirable.

Skills & Competencies

• Highly self-motivated and personable.
• Able to communicate effectively within a team environment.
• Able to organise daily tasks, to frequently work under pressure and to meet tight deadlines.
• Possess excellent attention to detail, performing work to an exceptionally high standard.
• Able to use initiative to solve problems and troubleshoot with the assistance of other members of the team.
• Should be computer literate with previous experience using Microsoft Office and LIMS.

Rewards & Benefits
Cyprotex aims to encourage, support and recognise the excellent performance and behaviour of our colleagues. Our performance-based compensation policy applies to all colleagues of the Evotec Group companies. We offer a variety of benefits and these include, amongst others, excellent pension benefits and service related holidays. We recognise that our colleagues have full lives away from the workplace and support working patterns that balance private life and career.

Career Development
As part of the Evotec Group, we grow through innovation, collaboration, nurturing our people and continuing to develop as a world-class organisation.

Our work is challenging and requires the most competent staff, therefore we aim to recruit and retain the best. We look for talented individuals from all walks of life, educational backgrounds and nationalities to provide the expertise and dedication to enable us to continually achieve success in all that we do. We offer equal opportunities for people with or without, visible or not-visible disabilities.

If you are keen to be a part of our successful and growing global business, please upload an up-to-date CV and covering letter using the following link:

Submit your application here

Direct applications only - no agencies please.

Evotec is a global, publicly listed biotechnology company with more than 2,100 employees at 13 sites, our headquarters are located in Hamburg. We do research on innovative approaches to drug discovery and development for and with leading pharmaceutical and biotechnology companies and academic institutions. By assembling top-class scientists, state-of-the-art technologies as well as substantial experience and expertise in key therapeutic areas including neuroscience, diabetes and complications of diabetes, pain and inflammation, oncology and infectious diseases, Evotec has established a unique leading position.

Cyprotex US, an Evotec Group, is looking for an Associate Scientist (Cell Biologist) based in Watertown, MA to assume responsibility for the routine screening of compounds in various in vitro ADME assays and reporting to the Associate Director or Senior Scientist.

Principal Accountabilities:
· Design molecular or cellular laboratory experiments, oversee their execution, and interpret results.
· Conduct research on cell function, including mechanisms of gene expression, cell signaling, or cell differentiation.
· Compile and analyze molecular or cellular experimental data and adjust experimental designs as necessary.
· Prepare scientific or technical reports or presentations.
· Perform laboratory procedures following protocols including deoxyribonucleic acid (DNA) sequencing, cloning and extraction, ribonucleic acid (RNA) purification, or gel electrophoresis.
· Develop or perform assays that monitor cell characteristics.
· Monitor or operate specialized equipment such as gas chromatographs and high pressure liquid chromatographs, electrophoresis units, thermocyclers, fluorescence activated cell sorters, and phosphorimagers.
· Coordinate molecular or cellular research activities with scientists specializing in other fields.
· Evaluate new supplies and equipment to ensure operability in specific laboratory settings.
· Confer with vendors to evaluate new equipment or reagents or to discuss the customization of product lines to meet user requirements.
· Maintain accurate laboratory records and data.

Basic Qualifications:
• A minimum of a Bachelor’s degree in biology, chemistry, or related discipline
• A minimum of one year of laboratory-based industrial or academic experience • Previous exposure to in vitro pharmacology (preferred), including but not limited to cellular assays as well as high throughput screening platforms and assays. Priority will be given to candidates with demonstrated experience in drug-drug interaction and transporter assays.
• Experience and/or comfort working with biological samples and cell lines
• A self-motivated and pro-active attitude, with the ability and desire to multi-task
• Solid work ethics and demonstrated record of productivity
• A results-driven mentality with a sense of urgency and commitment to the goals of our mission
• Ability to focus and pay attention to detail
• Recognize and troubleshoot data anomalies to maintain high data quality (after appropriate training, if required)
• Intermediate/advanced experience with MS Office and ability to learn new software
• Excellent problem solving, organizational and experimental management skills
• Strong written and verbal communication skills
• Commitment to help the team achieve deliverables and meet aggressive timelines
• Ability to be both independent as well as effectively interact with team members and work in a highly dynamic and collaborative environment

Cyprotex, an Evotec Group, is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, gender, age, disability, genetic information, gender expression, gender identity, national origin, religion, sexual orientation, or veteran status.

To apply for this position please upload your CV and a covering letter to the website @www.evotec.com via the following link:

Submit your application here

Evotec is a global, publicly listed biotechnology company with more than 2,100 employees at 13 sites, our headquarters are located in Hamburg. We do research on innovative approaches to drug discovery and development for and with leading pharmaceutical and biotechnology companies and academic institutions. By assembling top-class scientists, state-of-the-art technologies as well as substantial experience and expertise in key therapeutic areas including neuroscience, diabetes and complications of diabetes, pain and inflammation, oncology and infectious diseases, Evotec has established a unique leading position.

Cyprotex, an Evotec Group, has an opportunity for an experienced scientist to join our in vitro toxicology/biological screening team based in Watertown, MA. The successful candidate will be responsible for managing and running Cell Based assays for in vitro toxicology.

Experience and knowledge
BS, MS or PhD trained with 3-5 years industry experience in the field of in vitro biology. This may be High Content Screening, cell based electrophysiology, or assay development.
Ability to work in a fast-paced, team environment with a good appreciation of deadlines and customer service.
Excellent written and verbal communication skills.
The ability to make decisions, troubleshoot and work independently.
Prior experience working in a CRO a plus.

Principal Accountabilities
To manage internal in vitro biology projects and client studies ensuring all work is performed to ahigh standard within expected timelines
To train and develop staff in experimental and scientific processes and provide scientific direction.
To lead and drive the implementation, validation, and development of new assay services and technologies.
To liaise with external customers to co-ordinate transfer of information and compounds between customer and Cyprotex.
To co-ordinate with the other Scientists to ensure consistent and effective management of internal projects, such as assay development, and external studies.
To assist development of the business in securing new customers by providing high quality science knowledge to potential customers in addition to raising the scientific profile of Cyprotex.

Skills and Competencies
In-depth knowledge of High Content Screening (Arrayscan) and other cell based assay platforms Some Knowledge of Microelectrode Array electrophysiology platforms
Practical experience in Assay Development Ability to troubleshoot and find solutions to problems
Communicates proactively and regularly Ability to effectively time manage Highly proficient in Microsoft Word, Excel, and other scientific software

Cyprotex, an Evotec group, is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, gender, age, disability, genetic information, gender expression, gender identity, national origin, religion, sexual orientation, or veteran status.

To apply for this position please upload your CV and a covering letter to the website ay www.evotec.com using the following link:

Submit your application here

Visit the Evotec website to see the current vacancies

https://recruitment.evotec.com/Vacancy.aspx