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- ADME PK
- ADME PK
- In Vitro Metabolism
- In Vitro Metabolism overview
- Reaction Phenotyping
- Cytochrome P450 Induction
- Relative Induction Score
- Cytochrome P450 (CYP) Inhibition (IC50)
- Cytochrome P450 Inhibition (Ki)
- Hepatocyte Stability
- Low Clearance HµREL Co-culture
- Low Clearance Hepatocyte Stability
- Hepatic Uptake Assay
- Metabolite Profiling and Identification
- Plasma Stability
- Microsomal Stability
- Microsomal Binding
- S9 Stability
- Time Dependent CYP Inhibition (single point)
- Time Dependent CYP Inhibition (IC50 shift)
- Time Dependent CYP Inhibition (kinact/KI )
- PXR and AhR Nuclear Receptor Activation
- UGT Inhibition
- In Vitro Permeability and Drug Transporter Services
- In Vitro Permeability and Drug Transporter Services overview
- PAMPA
- Caco-2 Permeability
- MDCK-MDR1 Permeability
- P-gp Substrate Identification
- BCRP Substrate Identification
- Human SLC Transporter Substrate Identification
- Human MRP Transporter Substrate Identification
- Preclinical Hepatic Oatp Substrate Identification
- P-glycoprotein Inhibition Service
- BCRP Inhibition Service
- Human SLC Transporter Inhibition
- BSEP, MRP2, MRP3 and MRP4 Inhibition
- Preclinical Hepatic Oatp Transporter Inhibition
- Non-CYP Mediated Metabolism
- Protein Binding
- Bioanalysis
- High Throughput ADME
- DDI Packages
- Prodrug Services
- Toxicology
- Toxicology
- 3D Microtissue Models
- Mitochondrial Toxicity
- Multiparametric Toxicity
- Immunotoxicology
- Genotoxicity
- Hepatotoxicity and Drug-induced Liver Injury (DILI)
- Hepatotoxicity and Drug-induced Liver Injury (DILI) overview
- CellCiphr® Premier
- Genotoxicity
- Transcriptomics Services
- Mitochondrial Toxicity
- Cytochrome P450 Time Dependent Inhibition (IC50 Shift)
- Reactive Metabolite Assessment
- BSEP, MRP2, MRP3 and MRP4 Inhibition
- Lysosomal Trapping
- Drug Induced Phospholipidosis & Steatosis Assay
- Cytotoxicity Screening Panel
- 3D Hepatotoxicity Assay using HepaRG Spheroids
- Mechanistic Toxicity
- Mechanistic Toxicity overview
- Cell Stress Panel
- Apoptosis and Necrosis Assay (Flow Cytometry)
- Phospholipidosis and Steatosis
- Lysosomal Trapping
- Hemolysis
- DILIsym collaboration
- Reactive Metabolite
- Toxicological Gene Regulation
- Cell Viability
- KeratinoSens™ Skin Sensitization
- Androgen Receptor Modulation
- Phototoxicity
- Nephrotoxicity
- Neurotoxicity
- Cardiotoxicity
- Drug-Drug Interactions
- Non-GLP Exploratory Toxicology
- Customized Toxicology Service
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Guides
Cyprotex have constructed easy-to-follow guides in the area of ADME, drug-drug interactions and mechanisms of toxicology. All our guides are free to order as hardcopies. Our ADME guide is also available to view online.
DDI Regulatory Guide
Download or order your FREE hardcopy of our DDI Guide
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Mechanisms of Drug-Induced Toxicity Guide
Download or order your FREE hardcopy of our Mechanisms of Drug-Induced Toxicity Guide
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