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Presentations

Evaluation of Pilocarpine in Multiple Neuronal Cell Types Using Microelectrode Array - Oral presentation SPS 2018
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Transporter DDI - An Evaluation of Approaches and Methodologies
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Uncertainty and Variability in High Throughput Toxicokinetics for Risk Prioritization
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The development and characterisation of 3D neuronal microtissues for safety testing
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DMG 2017 In vitro 3D toxicology models
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Incosmetics_Skin Metabolism Presentation_April 2017
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Methods to evaluate in vitro models of skin metabolism
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Development of 3D cardiac and hepatic microtissue models for the improved prediction of clinical cardio- and hepatotoxicity
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A Novel in vitro Neurotoxicity Assay that Accurately Predicts Seizurogenic Compounds
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Utilization of In Vitro Mechanistic and 3D Models to Improve the Prediction of Hepatotoxicity and Cardiotoxicity
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A novel in vitro neurotoxicity assay that accurately predicts seizurogenic compounds
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eCiphrCardio and eCiphrNeuro: Assessing Toxicity using a Microelectrode Array
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Cyprotex DDI Webinar 19 Jul 2012
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2012 DMDG Open Meeting:Comparison of in vitro approaches using high content screening to investigate metabolism-mediated toxicity
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Advances in Mechanistic High Content Toxicology Webinar
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The Role of In Vitro Assays in Determining Metabolite-Mediated Toxicity
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'Physicochemical Properties and their Relation to ADMET' webinar – PDF VERSION
15th May 2013
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'Physicochemical Properties and their Relation to ADMET' webinar – AUDIO VERSION
15th May 2013
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The Evolution of in vitro ADME-Tox Screening - A 20 year Perspective
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New Screening Approach for Assessing Neuronal Activity and Neurotoxicity
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Understanding species and tissue-dependent differences in carboxylesterase-mediated metabolism
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Cyprotex 4th European Drug Discovery Workshop 2010: Transporters and cytochrome P450 interplay in defining hepatic drug clearance by Professor Brian Houston (Director of the Centre for Applied Pharmacokinetic Research, University of Manchester)
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Cyprotex 4th European Drug Discovery Workshop 2010: Variations in permeability assays and their potential issues by Dr. Kevin Weigl (Senior Scientist, Abbott Products GmbH)
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Cyprotex 4th European Drug Discovery Workshop 2010: Insoluble substances in in-vitro assays by Dr. Christa Kneip (Senior Scientist, Grünenthal)
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In a Virtual World, Where Are the Walls of the House? The New Outsourcing.
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eCiphrCardio - Assessing Cardiotoxicity through field potential using a Microelectrode Array
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A Combination of Standard and Innovative Technologies for Translational ADME-Tox Science
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Cyprotex 4th European Drug Discovery Workshop 2010: Special considerations of compound in vitro profiling during fast progression to clinical phases by Dr. Constance Höfer (Founder and Chief Scientist, DMPKORE)
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Cyprotex 4th European Drug Discovery Workshop 2010: Physiologically based pharmacokinetic/ pharmacodynamic modelling for lead optimisation of CNS-Active therapeutics by Dr. Simon Thomas (Head of Scientific Computing, Cyprotex Discovery)
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Cyprotex 5th NA Drug Discovery Workshop 2010: The role of hepatic and renal uptake transporters in drug discovery and development by Dr. Sonia de Morais (Director of DMPK, Abbott Labs)
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Cyprotex 5th NA Drug Discovery Workshop 2010: Targeted solutions to DMPK problems: avoiding unnecessary screening by Dr. Bernard Murray (Senior Research Scientist I, Gilead)
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Cyprotex 5th NA Drug Discovery Workshop 2010: Metabolite identification in drug discovery by Dr. Ron Aoyama (Senior Scientist I-DMPK, Exelixis)
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Cyprotex 5th NA Drug Discovery Workshop 2010: PBPK modelling for the intergration of ADME data during drug discovery
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Cyprotex 5th NA Drug Discovery Workshop 2010: Research strategies in LG and LO: combining in vitro and in vivo ADME approaches by Dr. Norman Huebert (Team Leader & Research Fellow ADME, Johnson & Johnson)
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Cyprotex 5th NA Drug Discovery Workshop 2010: Drug metabolism in gut microbiota: a case study involving a pyridine N-oxide compound by Dr. Shichang Miao & Tim Stratton (Director DMPK, ChemoCentryx & Scientist, ChemoCentryx
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Cyprotex 5th NA Drug Discovery Workshop 2010: Comparison of strategies for assessing metabolic stability in vitro
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Cyprotex 5th NA Drug Discovery Workshop 2010: P-gp based drug interactions at the blood-brain barrier: Fact or fantasy? by Peng Hsiao (Research Assistant, University of Washington)
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Cyprotex 4th NA Drug Discovery Workshop 2009: Physiologically Based Pharmacokinetics Modelling
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Cyprotex 4th NA Drug Discovery Workshop 2009: Identification of reactive metabolites in early drug discovery
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LRIG New Jersey 2008 presentation: Improving candidate quality through the prediction of clinical outcome
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Cyprotex drug discovery workshop 2007 presentation: Identification of reactive metabolites in early drug discovery
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Cyprotex drug discovery workshop 2007 presentation: Screening for P-gp inhibition in vitro: Assays and implications
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