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in vitro toxicology

Non-GLP Exploratory Toxicology

Capabilities include:

  • Early assessment of drug safety risk

    • Exposure, toxicokinetics and tolerability studies
    • Dose range finding studies
    • Safety biomarkers (transcriptomics, proteomics, metabolomics, lipidomics)
    • Formulation assessment
  • Mechanistic toxicology studies

    • Histology
    • Haematology and biochemistry
    • mRNA analysis and upregulation in CYP activity
    • Protein expression analysis
    • Toxicogenetics
  • Proof of concept for drug mechanism of action or efficacy

    • Target engagement
    • Biomarkers

Our non-GLP exploratory toxicology services are carried out at Evotec’s French facility in Toulouse. 

Contact enquiries@cyprotex.com for more information

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ADME-Tox Guides Pricing & Discounts

Contact us to discuss your ADME Tox issues or request a quote

Telephone:
North America (East Coast): 888-297-7683
Europe: +44 1625 505100

 

or fill out the form below:

Please give details of the assays you are interested in. Where appropriate please specify one or more species (human, rat, mouse etc.), isoforms (CYP1A1,CYP1B1, etc) or other relevant details.

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